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1

High-level expression and bulk crystallization of recombinantl-methionine γ-lyase, an anticancer agent

Tomoaki Takakura, Takaomi Ito, Shigeo Yagi, Yoshihide Notsu, Takashi Itakura, Takumi Nakamura, Kenji Inagaki, Nobuyoshi Esaki, Robert M. Hoffman, Akio Takimoto

Journal:

Applied Microbiology and Biotechnology

Year:

2006

Language:

english

File:

PDF, 285 KB

english, 2006

2

Prominent isovolumic relaxation flow in a patient with cardiac tamponade

Ikuo Misumi, Kenji Ebihara, Ryuichiro Akahoshi, Taku Rokutanda, Masafumi Miyajima, Toshihiro Esaki, Mitsuhiro Matsumoto, Yoshihiko Hirota, Hisao Ogawa

Journal:

Journal of Echocardiography

Year:

2011

Language:

english

File:

PDF, 540 KB

english, 2011

3

Recent Topics in Pyridoxal 5'-Phosphate Enzyme Studies

Hayashi, Hideyuki, Wada, Hiroshi, Yoshimura, Tohru, Esaki, Nobuyoshi, Soda, Kenji

Journal:

Annual Review of Biochemistry

Year:

1990

Language:

english

File:

PDF, 874 KB

english, 1990

4

Evaluation of performance of the Omni mode for detecting video capsule endoscopy images: A multicenter randomized controlled trial

Hosoe, Naoki, Watanabe, Kenji, Miyazaki, Takako, Shimatani, Masaaki, Wakamatsu, Takahiro, Okazaki, Kazuichi, Esaki, Motohiro, Matsumoto, Takayuki, Abe, Takayuki, Kanai, Takanori, Ohtsuka, Kazuo, Watan

Journal:

Endoscopy International Open

Year:

2016

Language:

english

File:

PDF, 254 KB

english, 2016

5

SAE Technical Paper Series [SAE International 1985 SAE International Fall Fuels and Lubricants Meeting and Exhibition - (OCT. 21, 1985)] SAE Technical Paper Series - Change of ZnDTP in Engine Oils During Use

Kawamura, Masuhiko, Fujita, Kenji, Esaki, Yasuo, Moritani, Hiroshi

Year:

1985

Language:

english

File:

PDF, 705 KB

english, 1985

6

Predicting Fraction Unbound in Human Plasma from Chemical Structure: Improved Accuracy in the Low Value Ranges

Watanabe, Reiko, Esaki, Tsuyoshi, Kawashima, Hitoshi, Natsume-Kitatani, Yayoi, Nagao, Chioko, Ohashi, Rikiya, Mizuguchi, Kenji

Journal:

Molecular Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 4.97 MB

english, 2018

7

Concerns and side effects of azathioprine during adalimumab induction and maintenance therapy for Japanese patients with Crohn’s disease: a sub-analysis of a prospective randomized clinical trial (DIAMOND study)

Hisamatsu, Tadakazu, Matsumoto, Takayuki, Watanabe, Kenji, Nakase, Hiroshi, Motoya, Satoshi, Yoshimura, Naoki, Ishida, Tetsuya, Kato, Shingo, Nakagawa, Tomoo, Esaki, Motohiro, Nagahori, Masakazu, Mats

Journal:

Journal of Crohn's and Colitis

Year:

2019

Language:

english

File:

PDF, 943 KB

english, 2019

8

OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody

Ohmura, Hirofumi, Yamaguchi, Kyoko, Hanamura, Fumiyasu, Ito, Mamoru, Makiyama, Akitaka, Uchino, Keita, Shimokawa, Hozumi, Tamura, Shingo, Esaki, Taito, Mitsugi, Kenji, Shibata, Yoshihiro, Oda, Hisanob

Journal:

British Journal of Cancer

Year:

2020

Language:

english

File:

PDF, 1.82 MB

english, 2020

9

Tagâless patency capsule for suspected small bowel stenosis: A nationwide multicenter prospective study in Japan

Nakamura, Masanao, Watanabe, Kenji, Ohmiya, Naoki, Hirai, Fumihito, Omori, Teppei, Tokuhara, Daisuke, Nakaji, Konosuke, Nouda, Sadaharu, Esaki, Motohiro, Sameshima, Yukinori, Goto, Hidemi, Terano, Aki

Journal:

Digestive Endoscopy

Year:

2020

File:

PDF, 14.59 MB

2020

10

Crystallization and preliminary X-ray crystallographic studies ofL-2-haloacid dehalogenase fromPseudomonas sp. YL

Hisano, Tamao, Hata, Yasuo, Fujii, Tomomi, Liu, Ji-Quan, Kurihara, Tatsuo, Esaki, Nobuyoshi, Soda, Kenji

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1996

Language:

english

File:

PDF, 336 KB

english, 1996

11

Identification of tumor vascular antigens by monoclonal antibodies prepared from rat-tumor-derived endothelial cells

Iwao Ohizumi, Shin-ichi Tsunoda, Kenji Taniguchi, Hiroyuki Saito, Keiko Esaki, Keiichi Koizumi, Hiroo Makimoto, Yukiko Wakai, Junji Matsui, Yasuo Tsutsumi, Shinsaku Nakagawa, Naoki Utoguchi, Yoshiyuki

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 539 KB

english, 1998

12

Recent advances in enzymatic synthesis of amino acids

Nobuyoshi Esaki, Kenji Soda, Hidehiko Kumagai, Hideaki Yamada

Journal:

Biotechnology and Bioengineering

Year:

1981

File:

PDF, 30 KB

1981

13

Enzymatic preparation of D- and L-lactic acid from racemic 2-chloropropionic acid

Kenzo Motosugi, Nobuyoshi Esaki, Kenji Soda

Journal:

Biotechnology and Bioengineering

Year:

1984

Language:

english

File:

PDF, 191 KB

english, 1984

14

Enantioselective synthesis of D-selenomethionine with D-amino acid aminotransferase

Nobuyoshi Esaki, Hiroko Shimoi, Hidehiko Tanaka, Kenji Soda

Journal:

Biotechnology and Bioengineering

Year:

1989

Language:

english

File:

PDF, 286 KB

english, 1989

15

Catalytic action of L-2-halo acid dehalogenase on long-chain L-2-haloalkanoic acids in organic solvents

A. K. M. Quamrul Hasan, Harumi Takada, Nobuyoshi Esaki, Kenji Soda

Journal:

Biotechnology and Bioengineering

Year:

1991

Language:

english

File:

PDF, 303 KB

english, 1991

16

Direct tumorigenic conversion of human gallbladder carcinoma cells by v-src but not by activated c-H-ras oncogene

Takashi Tatsumoto, Shuji Nakano, Kenji Shimizu, Mayumi Ono, Taito Esaki, Koh-Ichi Ohshima, Yoshiyuki Niho

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 2.50 MB

english, 1995

17

Mechanistic studies of two amino acid racemases of broad substrate specificity from Pseudomonas striata and Aeromonas caviae

Kevin Reynolds, Jennifer Martin, Shu-Jane Shen, Nobuyoshi Esaki, Kenji Soda, Prof. Dr. Heinz G. Floss

Journal:

Journal of Basic Microbiology

Year:

1991

Language:

english

File:

PDF, 830 KB

english, 1991

18

Enzymatic preparation of α- and β-deuterated or tritiated amino acids with l-methionine γ-lyase

Nobuyoshi Esaki, Seiji Sawada, Hidehiko Tanaka, Kenji Soda

Journal:

Analytical Biochemistry

Year:

1982

Language:

english

File:

PDF, 361 KB

english, 1982

19

Purification of bacterial l-methionine γ-lyase

Toru Nakayama, Nobuyoshi Esaki, Kunio Sugie, Temir T. Beresov, Hidehiko Tanaka, Kenji Soda

Journal:

Analytical Biochemistry

Year:

1984

Language:

english

File:

PDF, 355 KB

english, 1984

20

A simple and efficient method for the oligonucleotide-directed mutagenesis using plasmid DNA template and phosphorothioate-modified nucleotide

Manabu Sugimoto, Nobuyoshi Esaki, Hidehiko Tanaka, Kenji Soda

Journal:

Analytical Biochemistry

Year:

1989

Language:

english

File:

PDF, 1.69 MB

english, 1989

21

Stereospecificity of hydrogen transfer by NADP-linked acyclic monoterpene primary alcohol dehydrogenase

Hiromitsu Ikeda, Shunji Nakai, Keiji Hashimoto, Shinichi Uesato, Nobuyoshi Esaki, Kenji Soda, Tetsuro Fujita

Journal:

Year:

1991

Language:

english

File:

PDF, 325 KB

english, 1991

22

The antiwear property of zinc dialkyldithiophosphates in used engine oils

Kenji Fujita, Yasuo Esaki, Masuhiko Kawamura

Journal:

Year:

1983

Language:

english

File:

PDF, 465 KB

english, 1983

23

A versatile bacterial enzyme: l-methionine γ-lyase

Hidehiko Tanaka, Nobuyoshi Esaki, Kenji Soda

Journal:

Enzyme and Microbial Technology

Year:

1985

Language:

english

File:

PDF, 744 KB

english, 1985

24

A simple method for determination of stereospecificity of aminotransferases for C-4′ hydrogen transfer of the coenzymes

Katsushi Nishimura, Junko Ito, Tohru Yoshimura, Nobuyoshi Esaki, Kenji Soda

Journal:

Bioorganic & Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 430 KB

english, 1994

25

Stereospecificity for the hydrogen transfer of pyridoxal enzyme reactions

Kenji Soda, Tohru Yoshimura, Nobuyoshi Esaki

Journal:

The Chemical Record

Year:

2001

Language:

english

File:

PDF, 537 KB

english, 2001

26

Bacterial assimilation ofd- andl-2-chloropropionates and occurrence of a new dehalogenase

Kenzo Motosugi, Nobuyoshi Esaki, Kenji Soda

Journal:

Archives of Microbiology

Year:

1982

Language:

english

File:

PDF, 541 KB

english, 1982

27

Overexpression and feasible purification of thermostable L-2-halo acid dehalogenase ofPseudomonassp. YL

Ji-Quan Liu, Tatsuo Kurihara, Vincenzo Nardi-Dei, Tokumitsu Okamura, Nobuyoshi Esaki, Kenji Soda

Journal:

Year:

1995

Language:

english

File:

PDF, 435 KB

english, 1995

28

Preparation of stereoselectively-deuterated NADH and NADPH by coupling of glutamate racemase and glutamate dehydrogenase

Nobuyoshi Esaki, Nobyuoshi Nakajima, Kaoru Nakamura, Kazuo Yonaha, Hidehiko Tanaka, Kenji Soda

Journal:

Biotechnology Letters

Year:

1990

Language:

english

File:

PDF, 280 KB

english, 1990

29

Phase II study of sequential treatment with S-1 and cisplatin for metastatic gastric cancer

Eishi Baba, Taito Esaki, Hiroshi Ariyama, Kenji Mitsugi, Tatsuma Morikita, Hiromitsu Fujishima, Hitoshi Kusaba, Shuji Nakano, Koichi Akashi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 295 KB

english, 2011

30

Oxaliplatin-induced allergic reaction in patients with colorectal cancer in Japan

Yoshihiro Shibata, Hiroshi Ariyama, Eishi Baba, Yasushi Takii, Taito Esaki, Kenji Mitsugi, Tanji Tsuchiya, Hitoshi Kusaba, Koichi Akashi, Shuji Nakano

Journal:

International Journal of Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 234 KB

english, 2009

31

Field trap test for bioassay of synthetic (1S,4R)-4-isopropyl-1-methyl-2-cyclohexen-1-ol as an aggregation pheromone ofPlatypus quercivorus(Coleoptera: Platipodidae)

Naoto Kamata, Kojiro Esaki, Kenji Mori, Hiroyuki Takemoto, Toru Mitsunaga, Hiroshi Honda

Journal:

Journal of Forest Research

Year:

2008

Language:

english

File:

PDF, 181 KB

english, 2008

32

Synthesis of l-selenodjenkolate and its degradation with methionine γ-lyase

Patrick Chocat, Nobuyoshi Esaki, Hidehiko Tanaka, Kenji Soda

Journal:

Analytical Biochemistry

Year:

1985

Language:

english

File:

PDF, 391 KB

english, 1985

33

Assay method for antitumor l-methionine γ-lyase: comprehensive kinetic analysis of the complex reaction with l-methionine

Tomoaki Takakura, Kenji Mitsushima, Shigeo Yagi, Kenji Inagaki, Hidehiko Tanaka, Nobuyoshi Esaki, Kenji Soda, Akio Takimoto

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 287 KB

english, 2004

34

Effect of 8-Methoxypsoralen Plus UVA on Psoriasis Leukotactic Factor.

Mizuno, Nobuyuki, Enami, Hisao, Esaki, Kenji

Journal:

The Journal of Investigative Dermatology

Year:

1979

File:

PDF, 1.48 MB

1979

35

Phase I/II study of a 3-week cycle of irinotecan and S-1 in patients with advanced colorectal cancer

Hitoshi Kusaba, Taito Esaki, Kitaro Futami, Sinnosuke Tanaka, Hiromitsu Fujishima, Kenji Mitsugi, Kenji Sakai, Hiroshi Ariyama, Risa Tanaka, Naoko Kinugawa, Takashi Ueki, Rhuichi Mibu, Eishi Baba, Shu

Journal:

Year:

2010

Language:

english

File:

PDF, 213 KB

english, 2010

36

High catalytic activity of alanine racemase from psychrophilic Bacillus psychrosaccharolyticus at high temperatures in the presence of pyridoxal 5′-phosphate

Yoko Okubo, Kumio Yokoigawa, Nobuyoshi Esaki, Kenji Soda, Haruo Misono

Journal:

FEMS Microbiology Letters

Year:

2000

Language:

english

File:

PDF, 198 KB

english, 2000

37

Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion

Esaki, Yoshiyasu, Li, Youxian, Matsuoka, Toshiyuki, Kuroiwa, Kenji, Sugimoto, Yukihiko, Narumiya, Shuh, Yao, Chengcan, Sakata, Daiji

Journal:

Nature Medicine

Year:

2009

Language:

english

File:

PDF, 657 KB

english, 2009

38

Vitamin B6 enzymes participating in selenium amino acid metabolism

Kenji Soda, Tadao Oikawa, Nobuyoshi Esaki

Journal:

Year:

1999

Language:

english

File:

PDF, 62 KB

english, 1999

39

Growth modulation of human tumor cells by a growth-inhibiting activity derived from tumorigenic V79 chinese hamster cells

Ichiro Ichinose, Shuji Nakano, Taito Esaki, Tatsuhiko Koga, Kenji Mitsugi, Hidenori Yamada, Yoshiyuki Niho

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1993

Language:

english

File:

PDF, 836 KB

english, 1993

40

Synthesis of optically active sulfur and selenium amino acids with microbial enzymes

Hidehiko Tanaka, Nobuyoshi Esaki, Kenji Soda

Journal:

Applied Biochemistry and Biotechnology

Year:

1985

Language:

english

File:

PDF, 598 KB

english, 1985

41

Phase II study of NK105, a paclitaxel-incorporating micellar nanoparticle, for previously treated advanced or recurrent gastric cancer

Ken Kato, Keisho Chin, Takaki Yoshikawa, Kensei Yamaguchi, Yasushi Tsuji, Taito Esaki, Kenji Sakai, Masami Kimura, Tetsuya Hamaguchi, Yasuhiro Shimada, Yasuhiro Matsumura, Ryuji Ikeda

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 155 KB

english, 2012

42

Phase 2 Study of Modified Irinotecan and Bolus 5-Fluorouracil/l-Leucovorin in Japanese Metastatic Colorectal Cancer Patients

Eishi Baba, Hiromitsu Fujishima, Akitaka Makiyama, Keita Uchino, Risa Tanaka, Taito Esaki, Hitoshi Kusaba, Kenji Mitsugi, Shuji Nakano, Koichi Akashi

Journal:

Advances in Therapy

Year:

2012

Language:

english

File:

PDF, 981 KB

english, 2012

43

S-(N-Methylthiocarbamoyl)-l-cysteine, a suicide substrate of l-methionine γ-lyase

Nobuyoshi Esaki, Tomio Kimura, Joji Goto, Toru Nakayama, Hidehiko Tanaka, Kenji Soda

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1984

Language:

english

File:

PDF, 501 KB

english, 1984

44

Gene cloning, purification and characterization of thermostable alanine dehydrogenase of Bacillus stearothermophilus

Yonekazu Sakamoto, Shinji Nagata, Nobuyoshi Esaki, Hidehiko Tanaka, Kenji Soda

Journal:

Journal of Fermentation and Bioengineering

Year:

1990

Language:

english

File:

PDF, 520 KB

english, 1990

45

Continuous conversion to optically pure l-methionine from d-enantiomer contaminated preparations by an immobilized enzyme membrane reactor

Nobuyoshi Nakajima, Dietrich Conrad, Hiroyuki Sumi, Kazuhiko Suzuki, Nobuyoshi Esaki, Christian Wandrey, Kenji Soda

Journal:

Journal of Fermentation and Bioengineering

Year:

1990

Language:

english

File:

PDF, 294 KB

english, 1990

46

Gene cloning, purification, and characterization of the highly thermostable leucine dehydrogenase of Bacillus sp.

Shinji Nagata, Haruo Misono, Susumu Nagasaki, Nobuyoshi Esaki, Hidehiko Tanaka, Kenji Soda

Journal:

Journal of Fermentation and Bioengineering

Year:

1990

Language:

english

File:

PDF, 494 KB

english, 1990

47

Total conversion of racemic 2-chloropropionic acid into d-lactate by combination of enzymatic and chemical dehalogenations

A.K.M. Quamrul Hasan, Kenzo Motosugi, Nobuyoshi Esaki, Kenji Soda

Journal:

Journal of Fermentation and Bioengineering

Year:

1991

Language:

english

File:

PDF, 126 KB

english, 1991

48

Synthesis of l-proline from the racemate by coupling of enzymatic enantiospecific oxidation and chemical non-enantiospecific reducation

Jeong Weong Huh, Kumio Yokoigawa, Nobuyoshi Esaki, Kenji Soda

Journal:

Journal of Fermentation and Bioengineering

Year:

1992

Language:

english

File:

PDF, 174 KB

english, 1992

49

Production of new tricarboxylic acid anhydrides from stearic acid by Pseudomonas cepacia A-1419

Shigeki Itoh, Nobuyoshi Esaki, Koichi Masaki, Wolfgang Blank, Kenji Soda

Journal:

Journal of Fermentation and Bioengineering

Year:

1994

Language:

english

File:

PDF, 384 KB

english, 1994

50

Large-scale production of thermostable alanine dehydrogenase from recombinant cells

Yonekazu Sakamoto, Hirosi Nakajima, Kazuhiko Nagata, Nobuyoshi Esaki, Kenji Soda

Journal:

Journal of Fermentation and Bioengineering

Year:

1994

Language:

english

File:

PDF, 341 KB

english, 1994